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Published in Volume 2, Issue 2 - 16. March 2015

Growth hormone administration patterns differently regulate epidermal growth factor signaling

Daniel Turyn

Affiliation: Facultad Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina

Keywords: Growth hormone, EGF Receptor, Cancer

Categories: Life Sciences

DOI: 10.17160/josha.2.2.21

Languages: English

Growth hormone (GH) is a pituitary hormone that stimulates longitudinal bone growth and induces diverse effects on cell growth, differentiation, and metabolism of proteins, lipids and carbohydrates (Herrington & Carter-Su 2001). The use of growth hormone in the endocrine practice and for the treatment of various clinical conditions is expanding. The first use of human GH (hGH) was replacement therapy in children with GH deficiency (GHD). However, further indications have been gradually approved or proposed since the development of recombinant human GH (rhGH).

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Comments

Gerhard G. Steinmann

16. Mar

A summary of an interesting pharmacokinetic/pharmacodynamic experiment with growth hormone. It would be great to see the experimental data.